| Risk Studies |
| Ballou, B., Lagerholm, B. C., Ernst, L. A., Bruchez, M. P. & Waggoner, A. S. (2004). Noninvasive imaging of quantum dots in mice. Bioconjugate Chemistry, 15, 79-86. |
| Derfus, A. M., Chan, W. C. W., Bhatia, S. N. 2003. Probing the cytotoxicity of semiconductor quantum dots. Nano Letters, 4(1), 11-18. |
| Dubertret, B., Skourides, P., Norris, D. J., Noireaux, V., Brivanlou, A. H. & Libchaber, A. (2002). In vivo imagine of quantum dots encapsulated in phospholipid micelles. Science, 28(5599), 1759-1762. |
| Green, M. & Howman, E. (2005). Semiconductor quantum dots and free radical induced DNA nicking. Chemical Communications, 1, 121-1213. |
| - NEW - Gagne, F.; Auclair, J.; Turcotte, P.; et al. (February 2008). Ecotoxicity of CdTe quantum dots to freshwater mussels: Impacts on immune system, oxidative stress and genotoxicity. Aquatic Toxicology, 86(3): 333-340. |
| Gopee, N.V., Roberts, D.W., Webb, P. et al.
(2007). Migration of Intradermally Injected Quantum Dots to Sentinel Organs in Mice. Toxicological Sciences, 98(1):249-257. Abstract. |
| Guo, G.N., Liu, W., Liang, J.G., He, Z.K., Xu, H.B., Yang, X.L. (April 2007). Probing the cytotoxicity of CdSe quantum dots with surface modification. Material Letters, 61(8-9): 1641-1644. Abstract. |
| Hardman, R. (2005). A toxicological review of quantum dots:
Toxicity depends on physico-chemical and environmental factors. Environmental
Health Perspectives, 114(2): 165-172.
Article |
| - NEW - Holbrook, RD; Murphy, KE; Morrow, JB; Cole, KD. (June 2008). Trophic transfer of nanoparticles in a simplified invertebrate food web. Nature Nanotechnology, 3(6): 352-355. Abstract |
| Hoshino, A., Hanaki, K., Suzuki, K., Yamamoto, K. (2004a). Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body. Biochemical and Biophysical Research Communications, 314, 46-53. |
| Hoshino, A., Fujioka, K., Oku, T., Suga, M., Sasaki, Y. F., Ohta, T., Hasuhara, M., Suzuki, K., & Yamamoto, K. (2004b). Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Letters, 4(11): 2163-2169. |
| Jaiswal, J. K., Mattoussi, H., Mauro, J. M., Simon, S. M., (2003). Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nature Biotechnology, 21, 47-51. |
| - NEW - Kennel, SJ; Woodward, JD; Rondinone, AJ; et al. (May 2008). The fate of MAb-targeted (CdTe)-Te-125m/ZnS nanoparticles in vivo. Nuclear medicine and biology, 35(4): 501-514. Abstract. |
| Larson, D. R., Zipfel, W. R., Williams, R. M., Clark, S. W., Bruchez, M. P., Wise, F. W., et al. (2003). Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science, 300(5624), 1434-1436. |
| - NEW - Li, HC; Zhou, QF; Liu, W; et al. (May 2008). Progress in the toxicological researches for quantum dots. Science in China Series B-Chemistry , 51(5): 393-400. Abstract. |
| Linse, S., Cabaleiro-Lago, C., Xue, W.F.(May 2007). Nucleation of protein fibrillation by nanoparticles. Proceedings of the National Academy of Sciences of the United States of America, 104(21): 8691-8696. Article |
| Lovrick, J., Bazzi, H.S., Cuie, Y., Fortin, G. R., Winnik, F. M. & Maysinger, D. (2005). Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots. Journal of Molecular Medicine, 83, 377-385. |
| Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan G., Wu, A. M., Gambhir, S. S. & Weiss, S. (2005). Quantum dots for live cells, in vivo imaging, and diagnostics. Science, 307, 538-544. |
| - NEW - Rouse, JG; Haslauer, CM; Loboa, EG, et al. (March 2008). Cyclic tensile strain increases interactions between human epidermal keratinocytes and quantum dot nanoparticles. Toxicol In Vitro, 22(2):491-7. Abstract. |
| Rushton, E. K., Oberdorster, G., & Finkelstein, J. (2005). Nanoparticles are capable of producing reactive oxygen species, upregulation of inflammatory cytokine expression and causing increased cytotoxicity. Paper presented at the 2nd International Symposium on Nanotechnology and Occupational Health. Oct. 3-6, Minneapolis, MN. |
| Ryman-Rasmussen, J.P., Riviere, J.E., and Monteiro-Riviere, N.A. (August 2006). Surface Coatings Determine Cytotoxicity and Irritation Potential of Quantum Dot Nanoparticles in Epidermal Keratinocytes. Journal of Investigative Dermatology, Abstract. Article |
| Ryman-Rassmussen, j.r., Riviere, J.E. & Monteiro-Riviere,
N.A. (2006). Penetration of intact skin by quantum dots with diverse
physiochemical properties. Toxicological Sciences. Prepublication online.
Abstract |
| Shiohara, A., Hoshino, A., Hanaki, K., Suzuki, K. & Yamamoto, K. (2004). On the cyto-toxicity caused by quantum dots. Microbiology and Immunology, 48 (9), 669-675. |
| Sweet, L., Strohm, B. (June 2006). Nanotechnology - Life-cycle risk management. Human and Ecological Risk Assessment, 12 (3): 528-551 |
| - NEW - Tang, M., Xing, T., Zeng, J. et al. (July 2008). Unmodified CdSe Quantum Dots Induce Elevation of Cytoplasmic Calcium Levels and Impairment of Functional Properties of Sodium Channels in Rat Primary Cultured Hippocampal Neurons. Environmental Health Perspectives, 116(7): 915-922. Abstract. |
| Voura, E. B., Jaiswal, J. K., Mattoussi, H., Simon, S. M. (2004). Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat. Med., 10, 993-998. |
| Yang, R.S.H., Chang, L.Z., et al. (September 2007). Persistent Tissue Kinetics and Redistribution of Nanoparticles, Quantum Dot 705, in Mice: ICP-MS Quantitative Assessment. Environmental Health Perspectives, 115(9): 1339-1343. Abstract. |
| - NEW - Zhang LW, Monteiro-Riviere NA. (June 2008). Assessment of quantum dot penetration into intact, tape-stripped, abraded and flexed rat skin. Skin Pharmacology and Physiology, 21(3):166-80. Abstract. |
| - NEW - Zhang LW, Yu WW, Colvin VL, Monteiro-Riviere NA. (April 2008). Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes. Toxicol Appl Pharmacol., 228(2):200-11. Abstract. |
| Zhang, TT; Stilwell, JL; Gerion, D; Ding, LH; Elboudwarej, O; Cooke, PA; Gray, JW; Alivisatos, AP; Chen, FF (April 2006). Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements. Nano Letters, 6 (4): 800-808. Abstract. Article |
| Zhang, Y., Chen, W., Zhang, J., Liu, J., Chen, G., Pope, C. (February 2007). In Vitro and In Vivo Toxicity of CdTe Nanoparticles. Journal of Nanoscience and Nanotechnology 7,2: 497-503 |
| Medical/Biological Imaging |
| Akerman, M. E., Chan, W. C. W., Laakkonen, P.., Bhatia, S. N., & Ruoslahta, E. (2002). Nanocrystal targeting in vivo. Proceedings of the National Academy of Sciences of the United States of America, 99(20), 12617-12621. |
| Alivisatos, P. (2004). The use of nanocrystals in biological detection. Nature Biotechnology, 22(1), 47-52. |
| Ballou, B., Lagerholm, B. C., Ernst, L. A., Bruchez, M. P., & Waggoner, A. S. (2004). Noninvasive imaging of quantum dots in mice. Bioconjugate Chemistry, 15, 79-86. |
| Dubertret, B., Skourides, P., Norris, D. J., Noireaux, V., Brivanlou, A. H. & Libchaber, A. (2002). In vivo imagine of quantum dots encapsulated in phospholipid micelles. Science, 28(5599), 1759-1762. |
| Gao, X., Cui, Y., Levelson, R. M., chung, L. W., et al.(2004). In vivo cancer targeting and imaging with semiconductor quantum dots. Nature Biotechnology, 22, 269-276. |
| Henry, C. (2003). Quantum dot advances—studies show that nanoparticles have potential biological application. Chemical Engineering News, 81, 10. |
| Hoshino, A., Hanaki, K., Suzuki, K., Yamamoto, K. (2004a). Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body. Biochemical and Biophysical Research Communications, 314, 46-53. |
| Jaiswal, J. K., Mattoussi, H., Mauro, J. M., Simon, S. M., (2003). Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nature Biotechnology, 21, 47-51. |
| Kleopfer, J. A., Mielke, R. E., Wong, M. S., Nealson, K. H., Stucky, G. & Nadeau, J. L. (2003). Quantum dots as strain- and metabolism-specific microbiological labels. Applied Environmental Microbiology, 69(7), 4205-4213. |
| Larson, D. R., Zipfel, W. R., Williams, R. M., Clark, S. W., Bruchez, M. P., Wise, F. W., et al. (2003). Water-soluble quantum dots for multiphoton fluerescence imaging in vivo. Science, 300(5624), 1434-1436. |
| Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan G., Wu, A. M., Gambhir, S. S. & Weiss, S. (2005). Quantum dots for live cells, in vivo imagine, and diagnostics. Science, 307, 538-544. |
| Pradhan, N., Battaglia, D.M., Liu, Y. and Peng,X. (January 2007). Efficient, Stable, Small, and Water-Soluble Doped ZnSe Nanocrystal Emitters as Non-Cadmium Biomedical Labels. Nano Letters. |
| Vashist, S.K., Tewari, R., Bajpai, R.P., Bharadwaj, L.M., and Raiteri, R. (September 2006). Review of Quantum Dot Technologies for Cancer Detection and Treatment. Azojono. Article |
| Voura, E. B., Jaiswal, J. K., Mattoussi, H., & Simon, S. M. (2004). Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat. Med. 10, 993-998. |
| Yacobi, NR; Phuleria, HC. et al. (December 2007). Nanoparticle effects on rat alveolar epithelial cell monolayer barrier properties. Toxicology in Vitro, 21(8): 1373-1381. |
